Xiaohua Huang Publications (> 39,000 citations)
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A machine learning-based investigation of integrin expression patterns in cancer and metastasis.
H. Shadman, S. Gomrokm, C. Litle, Q. Cheng, Y. Jiang, X. Huang, J.D. Ziebarth, and Y. Wang
Scientific Reports 2025, 15, 5270.
https://doi.org/10.1038/s41598-025-89497-w -
Magnetic-plasmonic core-shell nanoparticles: properties, synthesis and applications for cancer detection and treatment.
A.L. Rodriguez-Nieves, S. Shah, M.L. Taylor, M. Alle, and X. Huang.
Nanomaterials 2025, 15(4), 264. Review.
https://www.mdpi.com/2079-4991/15/4/264 - Single vesicle surface protein profiling and machine learning-based dual image analysis
for breast cancer detection.
M.L. Taylor, M. Alle, R. Wilson Jr., A. Rodriguez-Nieves, M.A. Lutey, W.F. Slavney, J. Stewart, H. Williams, K. Amrhein, H. Zhang, Y. Wang, T.B. Hoang, and X. Huang.
Nanomaterials 2024, 14(21), 1739. Editor's Choice Article, February 2025.
https://www.mdpi.com/2079-4991/14/21/1739
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Dialdehyde cellulose nanofibrils/polyquaternium stabilized ultra-fine silver nanoparticles for synergistic antibacterial therapy.
K.K. Gollapudi, S.D. Dutta, M. Adnan, M.L. Taylor, K.V.N.S. Reddy, M. Alle, and X. Huang
Int. J. Biol. Macromol. 2024, 4, 135971.
https://doi.org/10.1016/j.ijbiomac.2024.135971 - Plasmonic couplings in Ag-Au heterodimers.
S. Gomrok, B.K. Eldridge, E.A. Chaffin, J.W. Barr, X. Huang, T.B. Hoang, and Y. Wang.
J. Chem. Phys. 2024, 160, 144706
https://pubs.aip.org/aip/jcp/article-abstract/160/14/144706/3282054 -
Multiplexed surface protein detection and cancer classification using gap-enhanced magnetic-plasmonic core-shell Raman nanotags and machine learning algorithm.
A.L. Rodriguez-Nieves, M.L. Taylor, R.E. Wilson, B.K. Eldridge, S. Nawalage, A. Annamer, H. Miller, M. Alle, S. Gomrok, D. Zhang, Y. Wang, and X. Huang.
ACS Appl. Mater. Interfaces 2024, 16(2), 2041-2057.
https://pubs.acs.org/doi/10.1021/acsami.3c13921 - Nanomaterials for molecular detection and analysis of extracellular vesicles.
M.L. Taylor, A.G. Giacalone, K.D. Amrhein, R.E. Wilson, Y. Wang, and X. Huang.
Nanomaterials 2023, 13, 524. Review. Editor's Choice Article, March 2023.
https://www.mdpi.com/2079-4991/13/3/524 - Dual imaging single vesicle surface protein profiling and early cancer detection.
K.D. Amrhein, M.L. Taylor, R.E. Wilson, C.E. Gallops, A. Annamer, V. Vinduska, E.A. Kwizera, H. Zhang, Y. Wang, T.B. Hoang, and X. Huang.
ACS Appl. Mater. Interfaces 2023, 15(2), 2679-2692.
https://pubs.acs.org/doi/10.1021/acsami.2c19235 - Gold nanorod-assisted photothermal therapy and improved strategies.
M.L. Taylor, R.E. Wilson Jr., K.D. Amrhein, and X. Huang.
Bioengineering 2022, 9, 200. Review.
https://www.mdpi.com/2306-5354/9/5/200 - Exosomal surface protein detection with quantum dots and immunomagnetic capture for
cancer detection.
V. Vinduska, C.E. Gallops, R. O'Connor, Y. Wang, and X. Huang.
Nanomaterials 2021, 11, 1853.
https://www.mdpi.com/2079-4991/11/7/1853 - Insights on the coupling of plasmonic nanoparticles from near-field spectra determined
via discrete dipole approximations.
J.W. Barr, S. Gomrok, E. Chaffin, X. Huang, and Y. Wang.
J. Phys. Chem. C 2021, 125, 5260-5268.
https://pubs.acs.org/doi/10.1021/acs.jpcc.1c01071 - Immunomagnetic capture and multiplexed surface marker detection of circulating tumor
cells with magnetic multicolor surface-enhanced Raman scattering nanotags.
R.E. Wilson, R. O'Connor, E.A. Kwizera, B. Nooroozi, C.E. Gallops, B. Morshed, Y. Wang, and X. Huang.
ACS Appl. Mater. Interfaces 2020, 12, 47220-47232.
https://pubs.acs.org/doi/10.1021/acsami.0c12395 - Plasmon- assisted random lasing from a single mode fiber tip.
D.S. Khatri, Y. Li, J. Chen, A.E. Stocks, E.A. Kwizera, X. Huang, C. Argyropoulos, and T. Hoang.
Opt. Express 2020, 28(11), 16417-16426.
https://opg.optica.org/oe/fulltext.cfm?uri=oe-28-11-16417&id=431834 - Small mode volume plasmonic film-coupled nanostar resonators.
N. Charchi, Y. Li, M. Huber, E.A. Kwizera, X. Huang, C. Argyropoulos, and T. Hoang.
Nanoscale Adv. 2020, 2, 2397-2403.
https://pubs.rsc.org/en/content/articlelanding/2020/na/d0na00262c - Near-field and far-field optical properties of magnetic plasmonic core-shell nanoparticles
with non-spherical shapes: A discrete dipole approximation study.
S. Bhardwaj, J. Barr, E. Chaffin, X. Huang, and Y. Wang.
AIP Adv. 2019, 9, 025021.
https://pubs.aip.org/aip/adv/article/9/2/025021/1075901/ - Ratiometric optical nanoprobes enable accurate molecular detection and imaging.
X. Huang, J. Song, X. Huang, Y. Xiong, and X. Chen.
Chem. Soc. Rev. 2018, 47, 2873-2920. Review. Citations: 664.
https://pubs.rsc.org/en/content/articlelanding/2018/cs/c7cs00612h - Molecular detection and analysis of exosomes using surface enhanced Raman scattering
gold nanorods and a miniaturized device.
E.A. Kwizera, R. O'Connor, V. Vinduska, M. Wiliams, E.R. Butch, S.E. Snyder, X. Chen, and X. Huang.
Theranostics 2018, 8(10), 2722-2738. Citations: 222.
https://www.thno.org/v08p2722.htm - A synthetic disaccharide derivative of diphyllin, TAARD, activates human natural killer
cells to secrete interferon-gamma via toll-like receptor-medicated NF-kB and STAT3
signalling pathways.
L. Yi, L. Chen, X. Guo, T. Lu, H. Wang, X. Ji, J. Zhang, Y. Ren, P. Pan, A.D. Kinghorn, X. Huang, L.S. Wang, Z. Fan, M.A. Caligiuri, J. Yu.
Front Immunol. 2018, 9, 1509.
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.01509/full - Synthesis and properties of magnetic-optical core-shell nanoparticles.
E.A. Kwizera, E. Chaffin, Y. Wang, and X. Huang.
RSC Adv. 2017, 7, 17137-17153. Review.
https://pubs.rsc.org/en/content/articlelanding/2017/ra/c7ra01224a - Gold nanoparticle based platforms for circulating cancer marker detection.
X. Huang, R. O'Connor, and E.A. Kwizera.
Nanotheranostics 2017, 1(1), 80-102. Review.
https://www.ntno.org/v01p0080.htm - Dependence of SERS enhancement on the chemical composition and structure of Ag/Au
hybrid nanoparticles.
E. Chaffin, R. O'Connor, J. Barr, X. Huang, and Y. Wang.
J. Chem. Phys. 2016, 145, 054706.
https://pubs.aip.org/aip/jcp/article/145/5/054706/316487 - Size- and shape-controlled synthesis and properties of magnetic-plasmonic core-shell
nanoparticles.
E.A. Kwizera, E. Chaffin, X. Shen, J. Chen, Q. Zou, Z. Wu, Z. Gai, S. Bhana, R. O'Connor, L. Wang, H. Adhikari, S.R. Mishra, Y. Wang, and X. Huang.
J. Phys. Chem. C 2016, 120, 10530-10546. Citations: 121.
https://pubs.acs.org/doi/10.1021/acs.jpcc.6b00875 - Photosensitizer-loaded gold nanorods for near infrared photodynamic and photothermal
cancer therapy.
S. Bhana, R. O'Connor, J. Johnson, J.D. Ziebarth, L. Henderson, and X. Huang.
J. Colloid. Interface Sci. 2016, 469, 8-16.
https://www.sciencedirect.com/science/article/pii/S0021979716300911 - Nanotechnology for enrichment and detection of circulating tumor cells.
S. Bhana, Y. Wang, and X. Huang.
Nanomedicine 2015, 10(12), 1973-1990. Review.
https://www.futuremedicine.com/doi/10.2217/nnm.15.32 - Near infrared-absorbing gold nanopopcorns with iron oxide cluster core for magnetically
amplified photothermal and photodynamic cancer therapy.
S. Bhana, G. Liu, L. Wang, H. Starring, S.R. Mishra, G. Liu, and X. Huang.
ACS Appl. Mater. Interfaces 2015, 7, 11637-11647. Citations: 126.
https://pubs.acs.org/doi/10.1021/acsami.5b02741 - Dielectric properties and magnetoresistance behavior of polyaniline coated carbon
fabrics.
B. Qiu, J. Guo, Y. Wang, X. Wei, Q. Wang, D. Sun, M.A. Khan, D.P. Young, R. O'Connor, X. Huang, X. Zhang, B.L. Weeks, S. Wei, and Z. Guo.
J. Mater. Chem. C 2015, 3, 3989-3998.
https://pubs.rsc.org/en/content/articlelanding/2015/tc/c4tc02578d
- Cr (VI) removal by magnetic carbon nanocomposites derived from cellulose at different
carbonization temperatures.
B. Qiu, Y. Wang, D. Sun, Q. Wang, X. Zhang, B.L. Weeks, R. O'Connor, X. Huang, S. Wei, and Z. Guo.
J. Mater. Chem. A 2015, 3, 9817-9825.Citations: 134.
https://pubs.rsc.org/en/content/articlelanding/2015/ta/c5ta01227a - Multiwalled carbon nanotubes composited with palladium nanocatalysts for highly efficient
ethanol oxidation.
Y. Wang, Q. He, J. Guo, H. Wei, S. Bhana, X. Huang, Z. Luo, T. Shen, K. Ding, S. Wei, and Z. Guo.
J. Electrochem. Soc. 2015, 162(7), F755-F763.
https://iopscience.iop.org/article/10.1149/2.0751507jes - Carboxyl multi-walled carbon nanotubes stabilized palladium nanocatalysts with improved
methanol oxidation reaction.
Y. Wang, Q. He, J. Guo, H. Wei, S. Bhana, X. Huang, Z. Luo, T. Shen, K. Ding, S. Wei, and Z. Guo.
ChemElectroChem. 2015, 2(4), 559-570.
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/celc.201402378 - Electropolymeriized polypyrrole nanocoatings on carbon paper for electrochemical energy
storage.
H. Wei, Y. Wang, J. Guo, X. Yan, R. O'Connor, X. Zhang, N.Z. Shen, B.L. Weeks, X. Huang, S. Wei, and Z. Guo.
ChemElectroChem. 2015, 2(1), 119-126.
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/celc.201402258 - Integration of nanostructured dielectrophoretic device and surface enhanced Raman
probe for highly sensitive rapid bacteria detection.
F.R. Madiyar, S. Bhana, L. Swisher, C. Culbertson, X. Huang, and J. Li.
Nanoscale 2015, 7, 3726-3736. Citations: 111.
https://pubs.rsc.org/en/content/articlelanding/2015/nr/c4nr07183b - Impact of core dielectric properties on the localized surface plasmonic spectra of
gold-coated magnetic core–shell nanoparticles.
E. Chaffin, S. Bhana, R.T. O'Connor, X. Huang, and Y. Wang.
J. Phys. Chem. B 2014, 118(49), 14076-14084.
https://pubs.acs.org/doi/10.1021/jp505202k - Magnetic graphene oxide nanocomposites: nanoparticles growth mechanism and property
analysis.
Y. Wang, Q. He, H. Qu, X. Zhang, J. Guo, J. Zhu, G. Zhao, H.A. Colorado, J. Yu, L. Sun, S. Bhana, M.A. Khan, X. Huang, D.P. Young, H. Wang, X. Wang, S. Wei, and Z. Guo.
J. Mater. Chem. C 2014, 2, 9478-9488. Citations: 129.
https://pubs.rsc.org/en/content/articlelanding/2014/tc/c4tc01351d - Synergistic interactions between activated carbon fabric and toxic hexavalent chromium.
C. Xu, B. Qiu, X. Yan, H. Wei, X. Huang, Y. Wang, D. Rutman, D. Cao, S. Bhaba, S. Wei, and Z. Guo.
ECS J. Solid State Sci. Technol. 2014, 3, M1-M9.
https://iopscience.iop.org/article/10.1149/2.004403jss - Capture and detection of cancer cells in whole blood with magnetic-optical nanoovals.
S. Bhana, E. Chaffin, Y. Wang, S.R. Mishra, and X. Huang.
Nanomedicine 2014, 9(5), 593-606. Reported by International Invention Reserach Media.
https://www.futuremedicine.com/doi/10.2217/nnm.13.77 - Gold nanorods carrying paclitaxel for photothermal-chemotherapy of cancer.
F. Ren, S. Bhana, D.D. Norman, J. Johnson, L. Xu, D.L. Baker, A.L. Parrill, and X. Huang.
Bioconjugate Chem. 2013, 24, 376-386. Citations: 135.
https://pubs.acs.org/doi/10.1021/bc300442d - Synthesis and properties of near infrared-absorbing magnetic-optical nanopins.
S. Bhana, B.K. Rai, S.R. Mishra, Y. Wang, and X. Huang.
Nanoscale 2012, 4, 4939-4942. Reported by Chemistry World News, The Royal Society of Chemistry.
https://pubs.rsc.org/en/content/articlelanding/2012/nr/c2nr31291c - The golden age: gold nanoparticles for biomedicine.
E.C. Dreaden, A.M. Alkilany, X. Huang, C.J. Murphy, and M.A. El-Sayed.
Chem. Soc. Rev. 2012, 41, 2740-2779. Review. Citations: 4096.
https://pubs.rsc.org/en/content/articlelanding/2012/cs/c1cs15237h - Beating cancer in multiple ways using nanogold.
E.C. Dreaden, M.A. Mackey, X. Huang, B. Kang, and M.A. El-Sayed.
Chem. Soc. Rev. 2011, 40, 3391-3404. Review. Citations: 724.
https://pubs.rsc.org/en/content/articlelanding/2011/cs/c0cs00180e - Plasmonic photo-thermal therapy (PPTT).
X. Huang and M.A. El-Sayed.
Alexandria J. Med. 2011, 47, 1-9. Review. Citations: 548.
https://link.springer.com/article/10.1007/s10103-007-0470-x - A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals
and covalently conjugated peptide ligands.
X. Huang, X. Peng, Y. Wang, Y. Wang, D.M. Shin, M.A. El-Sayed, and S. Nie.
ACS Nano 2010, 4(10), 5887-5896. Citations: 523.
https://pubs.acs.org/doi/10.1021/nn102055s - Comparative studies of photothermolysis of cancer cells with nuclear-targeted or cytoplasm-targeted
gold nanospheres: continuous wave or pulsed lasers.
X. Huang, B. Kang, W. Qian, P.C. Chen, A.K. Oyelere, and M.A. El-Sayed.
J. Biomed. Opt. 2010,15(5), 058002/1-7. Citations: 148.
https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-15/issue-05/058002/Comparative-study-of-photothermolysis-of-cancer-cells-with-nuclear-targeted/10.1117/1.3486538.full
Before The University of Memphis: - Gold nanoparticles: optical properties and implementations in cancer diagnosis and
photothermal therapy.
X. Huang and M.A. El-Sayed.
J. Adv. Res. 2010, 1, 13-28. Review. Citations: 2622.
https://www.futuremedicine.com/doi/10.2217/17435889.2.5.681 - Dark-field light scattering imaging of living cancer cell component from birth to
division using bioconjugated gold nanoprobes.
W. Qian, X. Huang, B. Kang, and M.A. El-Sayed.
J. Biomed. Opt. 2010, 15(4), 046025/1-9. Citations: 116.
https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-15/issue-04/046025/Dark-field-light-scattering-imaging-of-living-cancer-cell-component/10.1117/1.3477179.full - Gold nanorods: from synthesis and properties to biological and biomedical applications.
X. Huang, S. Neretina, and M.A. El-Sayed.
Adv. Mater. 2009, 21 (48), 4880-4910. Review. Citations: 2290.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.200802789 - Gold nanoparticles surface plasmon field effects on the proton pump process of the
bacteriorhodopsin photosynthesis.
A. Biesso, W. Qian, X. Huang, and M.A. El-Sayed.
J. Am. Chem. Soc. 2009, 131(7), 2442-2443.
https://pubs.acs.org/doi/10.1021/ja8088873 - Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of HSC-3
tumors in mice.
E.B. Dickerson, E.C. Dreaden, X. Huang (co-first author), H. Chu, S. Pushpanketh, J.F. McDonald, and M.A. El-Sayed.
Cancer Lett. 2008, 269, 57-66. Citations: 1404.
https://www.sciencedirect.com/science/article/pii/S030438350800325X?via%3Dihub - Noble Metals on the Nanoscale: Optical and Photothermal Properties and Applications
in Imaging, Sensing, Biology, and Medicine.
P.K. Jain, X. Huang, I.H. El-Sayed, and M.A. El-Sayed.
Acc. Chem. Res. 2008, 41(12), 1578-1586. Review. Citations: 4923.
https://pubs.acs.org/doi/10.1021/ar7002804 - Plasmonic photothermal therapy using gold nanoparticles.
X. Huang, P.K. Jain, I.H. El-Sayed, and M.A. El-Sayed.
Lasers Med. Sci. 2008, 23(3), 217-228. Review. Citations: 2832.
https://link.springer.com/article/10.1007/s10103-007-0470-x - The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal
cancer therapy.
X. Huang, W. Qian, I.H. El-Sayed, and M.A. El-Sayed.
Lasers Surg. Med. 2007, 39, 747-753. Citations: 353.
https://onlinelibrary.wiley.com/doi/10.1002/lsm.20577 - Effect of plasmonic gold nanoparticles on benign and malignant cellular goldtofluorescence:
a novel probe for fluorescence based detection of cancer.
I.H. El-Sayed, X. Huang, F. Macheret, and R. Kramer.
Technol. Cancer Res. Treat. 2007, 6(5), 403-412.
https://journals.sagepub.com/doi/10.1177/153303460700600505 - Gold nanoparticles: interesting optical properties and recent applications in cancer
diagnostics and therapy.
X. Huang, P.K. Jain, I.H. El-Sayed, and M.A. El-Sayed.
Nanomedicine 2007, 2(5), 681-693. Review. Citations: 1828.
https://www.futuremedicine.com/doi/10.2217/17435889.2.5.681 - Peptide conjugated gold nanorods for nuclear targeting.
A.K. Oyelere, P.C. Chen, X. Huang, I.H. El-Sayed, and M.A. El-Sayed.
Bioconjugate Chem. 2007, 18, 1490-1497. Citations: 438.
https://pubs.acs.org/doi/10.1021/bc070132i - Cancer cells assemble and align gold nanorods conjugated to antibodies to produce
highly enhanced, sharp and polarized surface raman spectra: a potential cancer diagnostic
marker.
X. Huang, I.H. El-Sayed, W. Qian, and M.A. El-Sayed.
Nano Lett. 2007, 7(6), 1591-1597. Citations: 672.
https://pubs.acs.org/doi/10.1021/nl070472c - Review of some surface plasmon resonance-enhanced properties of noble metal nanoparticles
and their applications to biosystems.
P.K. Jain, X. Huang, I.H. El-Sayed, and M.A. El-Sayed.
Plasmonics 2007,2, 107-118. Review. .Citations: 1663.
https://link.springer.com/article/10.1007/s11468-007-9031-1 - Cancer cell imaging and photothermal therapy in the near-infrared region by using
gold nanorods.
X. Huang, I.H. El-Sayed, W. Qian, and M.A. El-Sayed. J. Am. Chem. Soc. 2006, 128 (6), 2115-2120. Reported by Georgia Tech News and Science Watch. ACS hot paper. #1 citation in Chemistry during period of Sept-Oct 2007. Evaluated as a priority paper by Nanomedicine. Citations: 6438.
https://pubs.acs.org/doi/10.1021/ja057254a - Determination of the minimum temperature required for selective photothermal destruction
of cancer cells with the use of immunotargeted gold nanoparticles.
X. Huang, P.K. Jain, I.H. El-Sayed, and M.A. El-Sayed.
Photochem. Photobiol. 2006, 82 (2), 412-417. Citations: 519.
https://onlinelibrary.wiley.com/doi/10.1562/2005-12-14-RA-754 - Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody
conjugated gold nanoparticles.
I.H. El-Sayed, X. Huang, and M.A. El-Sayed.
Cancer Lett. 2006, 239 (1), 129-135. Citations: 1817.
https://www.sciencedirect.com/science/article/pii/S0304383505007378 - Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated
gold nanoparticles in cancer diagnostics: applications in oral cancer.
I.H. El-Sayed, X. Huang, and M.A. El-Sayed.
Nano Lett. 2005, 5 (5), 829-834. Reported by Georgia Tech News. ACS hot paper. Citations: 2499.
https://pubs.acs.org/doi/10.1021/nl050074e - Gold nanoparticles: catalyst for the oxidation of NADH to NAD+.
X. Huang, I.H. El-Sayed, X. Yi, and M.A. El-Sayed.
J. Photochem. Photobiol. B 2005, 81, 76-83. Citations: 102.
https://www.sciencedirect.com/science/article/pii/S1011134405001259?via%3Dihub - Ultroviolet protection using intensity-dependent spectral shift in bacteriorhodopsin.
Y. Huang, J. Fu, D.J. Hagan, X. Huang, M.A. El-Sayed, and S.T. Wu.
IEEE J. Sel. Top. Quantum Electron. 2005, 11(4), 902-905.
https://ieeexplore.ieee.org/document/1545992 - Investigation of the structures of gamma-Al2O3-supported MgO by surface extended energy
loss fine structure.
X. Huang, H. Huang, D. Jiang, and B. Zhao.
J. Phys. Chem. A 2002, 106, 2815-2820.
https://pubs.acs.org/doi/pdf/10.1021/jp010712r - Investigation of the dispersion of MgO onto gamma-Al2O3 by SEELFS.
X. Huang, H. Huang, D. Jiang, and B. Zhao.
Modern Instrum. 2001, 1, 39-41. - Investigation of structure and chemical states of self-assembled gold nanoscale particles
by angle-resolved x-ray photoelectron spectroscopy.
X. Huang, H. Huang, N. Wu, R. Hu, T. Zhu, and Z. Liu.
Surf. Sci. 2000, 459, 183-190.
https://www.sciencedirect.com/science/article/pii/S0039602800004830 - Investigation of the structures of Mg-Al mixed oxides by SEELFS.
X. Huang, H. Huang, D. Jiang, and B. Zhao.
Acta Chim. Sinica 2000, 58, 909-911.
http://sioc-journal.cn/Jwk_hxxb/EN/abstract/abstract336194.shtml - Covalent attachment of gold nanoparticles onto the thiol-terminated surface through
Gold-S Bonding.
R. Hu, T. Zhu, Z. Liu, X. Huang, H. Huang.
Acta Phys.-Chim. Sinica 1999,15, 961-964.
https://www.whxb.pku.edu.cn/EN/abstract/abstract22964.shtml