Director, Bioinformatics Program
Ph.D. University of Houston
Post-doctoral Fellow, St. Jude Children’s Research Hospital, Memphis, TN
|Phone: (901) 678-1670
Fax: (901) 678-4457
|University of Memphis
429 Smith Hall
Memphis, TN USA 38152
My lab is investigating the molecular and cellular mechanisms of neuronal migration
and dendrite maturation during mammalian brain development. We are currently characterizing
the function of a novel GTPase activating protein, Disabled 2 Interacting Protein
(Dab2IP), during brain development using a mouse knock-out model and a variety of
biochemical, cellular, morphological and behavioral approaches.
My lab is investigating the physiological and pathophysiological role of amyloid precursor
protein (APP) and its family members, amyloid precursor like proteins 1 and 2, using
mouse knock-out models. Mutations in APP have been linked to early-onset Alzheimer’s
Disease, but very little is known about its physiological role in the brain. Currently,
we are using genomic, proteomic, and cell-based approaches to identify gene and protein
networks that are associated with APP family proteins.
My lab is developing text-mining approaches to automatically extract gene function
information from the biomedical literature abstracts to assist in interpretation of
high-throughput genomic studies.
Publications & Research
Dr. Ramin Homayouni, associate professor, director, Bioinformatics
Finding the causes of Alzheimer's Disease
Homayouni and team are making discoveries concerning interactions of proteins that cause Alzheimer's Disease with mitochondria within cells.
See the video